Staff Scientist, R&D

Natera · South San Francisco · Other

Posted 2026-07-29

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POSITION SUMMARY:

Initiates and executes pre-clinical scientific research and development in the Molecular Biology Research team. Focuses on advancing Natera’s transplant assessment portfolio and works within a research team inventing and evaluating new technologies for applications in transplant assessment, oncology, and NIPT. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plans and executes laboratory research.  Maintains broad knowledge of state-of-the-art principles and theories.

PRIMARY RESPONSIBILITIES:

Contributes substantially and intellectually to research or development

Performs duties largely independent from manager

Leads in-lab efforts to create and develop novel nucleic acid based diagnostic tests

Thoroughly comprehends the objectives and vision of the work

Independently develops plans, generates and advances new ideas

Independently designs and executes moderate to high complexity experiments

Coordinates the execution and analysis of effective experiments with statistics and bioinformatics teams

Performs basic data analysis (e.g. R, JMP, Excel)

Documents research progress under a Quality Management System

Interacts with on-site CLIA lab, Sequencing and Process Development groups

Works with partners and outside collaborations

Communicates progress directly with colleagues and senior management

This role works with PHI on a regular basis both in paper and electronic form and has access to various technologies to access PHI (paper and electronic) in order to perform the job

Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.

Must maintain a current status on Natera training requirements.

QUALIFICATIONS:

Degree in molecular biology, tissue or cellular biology, immunology or closely related field

Associate Scientist level: Bachelor’s degree or higher with a minimum of 6 years of industry experience

Scientist level: M.S with a minimum of 10 years of industry experience; or Ph.D. with a minimum of 8 years of industry experience

KNOWLEDGE, SKILLS, AND ABILITIES:

Must have experience with next generation sequencing (NGS) and DNA/RNA molecular biology.

Experience with nucleic acid technologies relating to PCR, qPCR, multiplex PCR, digital PCR, NGS and microarrays

Epigenetic/methylation, target enrichment, cfDNA/RNA and NGS data analysis experience is a plus

Track record of originating, developing and productizing novel nucleic acid techniques and tests

Strong research skills with a history of innovation

Experience developing tests in transplant assessment, oncology, NIPT or liquid biopsy a plus

Proven success in collaborative and individual projects

Demonstrated success in applying independent scientific judgment in experimental design and analysis

Very strong analytical and problem-solving skills

Adept with Excel and basic statistical analysis

Bioinformatic capabilities, programming (e.g. PERL, python) and databases experience (SQL) are a plus

Skilled at writing clear plans, reports and SOPs

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

Annual performance incentive bonus

Long-term equity awards

Comprehensive health benefits (medical, dental, vision)

401(k) with company match

Generous paid time off and company holidays

Additional wellness and work-life benefits

Compensation Range

$157,300—$196,600 USD

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