Sr Systems Administrator
Position Summary
Natera is looking for a Sr Systems Administrator to be the on-site go-to person for IT Infrastructure and Employee Care at our Boulder office. You'll be the person who keeps day-to-day operations running smoothly while serving as a local extension of our centralized IT Employee Care and Infrastructure team. This is a hands-on role that will own end-user support, site infrastructure, networking, and equipment connectivity for a site with roughly 25–75 people. You'll partner closely with our central IT group on configurations, standards, security, and larger projects. As the senior on-site IT resource, you'll operate a level above the day-to-day ticket queue — owning Level 2–3 escalations and acting as the local point of engagement and operational support for business and lab operations.
PRIMARY RESPONSIBILITIES:
Escalation & Employee Care
Own Level 2–3 escalations for the site, serving as the senior technical resource for complex issues beyond the L1 ticket queue.
Provision, image, deploy, and maintain laptops, desktops, and workstations.
Support and troubleshoot printers, peripherals, conference room / AV systems, and other office hardware.
Onboard and offboard local employees, including account, device, and access setup in coordination with central IT.
Engage off-hours support for site-critical issues and provide an on-site escalation backstop.
Infrastructure, networking & connectivity
Help support site networking alongside the Network Operations Team.
Act as remote hands to help troubleshoot switches, firewalls, Wi-Fi, and internet connections.
Manage connectivity for lab and specialized equipment, ensuring instruments and workstations stay reliably connected to the network.
Monitor site infrastructure and proactively address issues before they impact the team.
Site operations & leadership
Act as the on-site resource for infrastructure and employee care operations.
Partner with the centralized IT team to roll out standards, tools, security practices, and projects locally.
Manage local hardware inventory, procurement requests, and vendor relationships, including outsourced services
Manage building access, utilities, environmental safety, and local regulatory compliance.
Document local systems, processes, and runbooks.
QUALIFICATIONS:
7+ years in IT support / operations, with demonstrated growth from service desk to infrastructure and systems work.
Strong end-user support skills paired with solid infrastructure fundamentals.
Working knowledge of networking fundamentals: switches, firewalls, Wi-Fi, DNS/DHCP, VPNs, and ISP coordination.
Experience deploying and managing endpoints (laptops, desktops, workstations) and associated tooling (MDM/imaging).
Hands-on experience supporting enterprise systems such as Google Workspace, Zoom, and Atlassian. Familiarity with other enterprise business SaaS applications a plus
Experience owning Level 2–3 escalations and acting as a senior point of resolution above a first-line support queue.
Experience coordinating with offshore, managed, or outsourced support teams across time zones.
Self-directed and dependable — able to run a site independently while staying aligned with a central team.
Clear communicator who can support both technical and non-technical colleagues.
Experience in healthcare, life sciences, or other regulated industries preferred
Strategic and execution-oriented; able to think globally while acting locally.
Comfortable in both leadership and hands-on operational roles.
Excellent interpersonal skills for engaging internal stakeholders, external vendors, and customers.
Pragmatic, resourceful, and able to thrive in an entrepreneurial environment.
NICE TO HAVE:
Experience supporting lab, scientific, or specialized equipment connectivity.
Server, storage, or virtualization administration experience.
Exposure to security/compliance practices (endpoint security, access management).
Prior experience as a site lead.
Relevant certifications (e.g., Google Workspace Admin, CompTIA Network+/Security+, networking vendor certs).