Senior Research Associate, Cell Culture Team, Integrated Research

The Opportunity:

Revolution Medicines is seeking a highly motivated Senior Research Associate to join our Cell Culture Team and support early discovery programs. This is a hands-on laboratory role focused on generating high-quality cellular materials to enable critical go/no-go decisions. The ideal candidate is detail-oriented, collaborative, and thrives in a fast-paced discovery environment.

As the team and function grow, this role can offer meaningful opportunities for professional development and expanded responsibilities.

Key Responsibilities:

Perform routine mammalian cell culture, including expansion, maintenance, cryopreservation, and thawing of multiple cell lines.

Maintain accurate cell line inventory and experimental documentation using Benchling.

Respond to urgent, time-sensitive requests from discovery teams to support key program milestones.

Develop protocols and document experimental workflows and observations with high rigor.

Partner closely with cross-functional teams to assess cell line needs and deliver materials on defined timelines.

Contribute to a culture of transparent, proactive communication across teams.

Identify opportunities to improve efficiency, robustness, and scalability of cell culture workflows.

Required Skills, Experience and Education:

S./M.S. degree in Molecular Biology, Cell Biology, Cancer Biology, or related life science field with 3+ years of hands-on mammalian cell culture experience; biopharmaceutical or biotechnology industry experience preferred.

Demonstrated expertise in aseptic technique and mammalian cell culture, including:

Concurrent handling of multiple cell lines.

Media preparation with complex supplements.

DMSO dilution calculations and cryopreservation best practices.

Strong experience optimizing and troubleshooting mammalian cell culture systems.

Familiarity with cell culture quality control practices (e.g., mycoplasma testing, cell line authentication).

Proficiency with electronic lab notebooks (e.g., Benchling) for experiment documentation, inventory management, and workflow execution.

Excellent organizational skills with meticulous attention to detail and data integrity.

Strong written and verbal communication skills; ability to work independently while collaborating effectively across teams.

Ability to prioritize work, meet deadlines, and remain composed in a dynamic, fast-paced environment.

Familiarity with standard laboratory equipment (microscopes, pipettes, centrifuges, cell counters).

A positive, flexible, and collaborative mindset with a continuous improvement mentality.

Preferred Skills:

Experience working with cancer cell lines, primary cells, or genetically engineered cell lines.

Experience with viral and non-viral transduction or transfection methods (e.g., lentivirus, retrovirus, lipid-based systems).

Hands-on experience with 2D and 3D cell culture systems, including spheroids and/or organoid models.

Exposure to cell-based assay development and downstream applications (e.g., viability, proliferation, reporter assays).

Experience supporting early discovery or translational research programs.

Experience in regulated or semi-regulated laboratory environments with strong documentation standards.

Exposure to automation, high-throughput cell culture, or scale-up workflows.

#LI-SB1 #LI-Onsite

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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Base Pay Salary Range

$106,000—$126,000 USD