Associate Director, Clinical Science

POSITION SUMMARY:

Join Natera as the Associate Director, Clinical Scientist in Oncology. You will execute clinical development strategies for our early cancer detection and cell-free DNA (cfDNA) In Vitro Diagnostic (IVD) portfolio, driving the design and execution of rigorous clinical studies that directly impact patient care. Every sample represents a real person, and you will take ownership of study activities, clinical strategy, and the timely delivery of high-quality data.

PRIMARY RESPONSIBILITIES:

Develop rigorous study concepts, including study design, schedule of assessments, objectives/endpoints, and eligibility criteria

Integrate stakeholder feedback and direct protocol authoring; use data to respond to health authority feedback

Support regulatory interactions and author clinical sections for regulatory correspondence and submissions, including briefing documents, presentations, and Investigational Device Exemption (IDE), IND, and NDA filings

Provide protocol training and contribute directly to Case Report Form (CRF) design

Ensure study manuals align with the protocol and engage investigators directly in study design methodology to ensure alignment with research objectives

Actively participate in pre-site selection discussions, site initiation visits, and investigator meetings to drive successful study execution

Contribute to and oversee real-time clinical data reviews, including the rigorous oversight of Contract Research Organizations (CROs) when applicable

Participate in the review and management of safety reports and submissions, treating quality as foundational

Support project teams with the conduct of clinical studies, including trials registration, results reporting, and the monitoring of emerging clinical and safety data trends

Consult on data management deliverables, clinical monitoring activities, interim analyses planning, and Data Safety Monitoring Board or Steering Committee meetings

Serve as a clinical science representative in internal and external meetings, pushing for clarity and action

Deliver unvarnished, data-backed updates on clinical timelines to senior management, pushing for clarity and outcome-driven decisions to meet program milestones

Support advisory boards and deliver direct, scientific presentations.

Drive clinical research plans, spanning company and investigator-initiated studies

Think team by partnering directly with senior leaders across functions to optimize clinical development and drive strategic execution without needing translation layers

Build data-driven, strategic relationships with Key Opinion Leaders (KOLs), consortiums, and clinical sites

Develop Standard Operating Procedures (SOPs) and analyze complex data.

Ensure strict compliance with HIPAA/PHI regulations and maintain all training requirements

Adapt to evolving clinical needs, taking ownership of tasks that move the work forward without waiting for a finished playbook

QUALIFICATIONS:

Ph.D., RN, MS, or B.S. in a scientific field; advanced degree preferred (MS, PharmD, MD, or PhD)

8–10+ years of clinical research experience, including 3–5+ years in a management role

Experience in oncology and early cancer detection is highly preferred

Experience with project management, clinical research execution, and rigorous scientific writing

Experience with In Vitro Diagnostics (IVD) is a plus

Deep knowledge of regulatory standards and Good Clinical Practices (GCP) is required

KNOWLEDGE, SKILLS, AND ABILITIES:

Think analytically, testing assumptions with data to troubleshoot and solve complex problems

Clear, direct oral and written communication skills with rigorous attention to detail

Think team by pulling cross-functional partners into the work, operating seamlessly across boundaries to advance clinical objectives

Proficiency with Google Workspace and Microsoft Office suites

Operate with pace and precision as the science, product surface, and business continue to evolve

Execution-focused leadership and a rigorous work ethic

Apply business knowledge, exercise data-driven judgment, and escalate issues without hesitation

Rigorous project management, organizational, and interpersonal skills.

Apply an ownership mindset, using data to push for action, close gaps, and deliver clinical outcomes

Demonstrate strategic and flexible thinking to untangle ambiguous problems and deliver actionable solutions

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$172,100—$215,150 USD