Principal Product Manager, Core AI

Opportunity

We are building a new interface to health: the Digital Twin.

The Digital Twin is a living, real-time model of each member’s metabolism and behavior—continuously learning from sensors, meals, sleep, movement, labs, and daily choices. It detects patterns, anticipates what’s coming, and guides members toward better health through timely, personalized actions.

To the member, it feels like a single, ever-present guide.

Under the hood, it’s a coordinated system of AI agents and human care working as one.

We’re looking for a Principal Product Manager to help define and build the core intelligence system at the heart of Twin.

This role sits at the intersection of:

LLMs and agent systems

Human + AI orchestration

Real-time health guidance

Voice and conversational interfaces

Platform and developer ecosystems

You will:

Define how the Digital Twin behaves across text, voice, and proactive experiences

Build specialized sub-agents that plug into the core Digital Twin

Create the platform and primitives that enable teams across Twin to build agents safely and quickly

Push the boundaries of what’s possible with modern AI systems in healthcare

Responsibilities

Define the Digital Twin intelligence system

Translate the core loop—Sense → Understand → Decide → Act → Learn—into a scalable agent system

Define how the Digital Twin reasons, responds, escalates, and coordinates across experiences

Shape the future of AI-driven health guidance across text, voice, and proactive interactions

Build specialized agent systems

Sensor intelligence

Scheduling and coordination

Nutrition

Exercise, sleep, and stress

Insights

App help and operational support

Care-team interaction orchestration

Build the platform that enables the company

Create the foundations that allow PMs and teams to build on top of the Digital Twin

Establish primitives for:

Agent creation and orchestration

Memory and personalization

Evaluation and monitoring

Define next-generation conversational experiences

Build deeply personalized experiences across chat, two-way voice, and ambient guidance

Define conversation patterns and interaction models that feel natural, trusted, and useful

Operate at frontier speed

Rapidly move from insight → prototype → experiment → production

Partner deeply with AI Engineering, Design, Clinical, and Product teams

Continuously evaluate emerging capabilities across LLMs, speech, memory, and agent systems

Establish metrics and evaluation systems for:

Guidance quality

Conversation effectiveness

Problem resolution

Behavior change

Other duties as assigned.

Qualifications

8+ years in Product Management (or equivalent impact), including significant experience building AI-native products

3+ years building and shipping products powered by:

LLMs

Agents

RAG

Personalization systems

Track record of owning complex, system-level products

Experience shipping conversational or voice experiences with measurable impact

Strong product judgment and analytical instincts:

Experimentation

Evaluation design

KPI definition

Builder mindset—you move from concept to shipped system quickly

Compensation and Benefits

The compensation range for this position is $205,000 - $240,000 annually.

Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. We are committed to delivering an outstanding culture and experience for every Twin employee through a company based on the values of passion, talent, and trust. We offer comprehensive benefits and perks in line with these principles, as well as a high level of flexibility for every Twin

A competitive compensation package in line with leading technology companies

A remote and accomplished global team

Opportunity for equity participation

Unlimited vacation with manager approval

16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents

100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options

401k retirement savings plan

Salary range for US jobs

US Salary Range

$205,000—$240,000 USD