Senior Director of Trade and Channel Management

Olema · San Francisco, California · Other

Posted 2026-07-25

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About the Role >>> Senior Director of Trade and Channel Management

As the Senior Director of US Trade and Channel Management reporting to the Vice President of Market Access, you will be responsible for the strategic design, implementation, and optimization of a high-performing distribution network that ensures patient access while maximizing commercial value.

As a key leader within the U.S. Market Access function, you will oversee the total distribution ecosystem, including Specialty Pharmacy, Distribution and 3PL, while driving the long-term roadmap for trade operations and ensuring the organization is positioned to scale for future therapeutic innovations.

This role is based out of either our Boston or San Francisco office and will require approximately 20% travel.

Your work will primarily encompass:

Strategic Trade & Distribution Architecture

Define and lead the long-term U.S. distribution strategy and the design of a distribution network to support the launch of our future oncology product(s), including a selection process to select key externals partners (ie. SP, SD, 3PL, etc)

Provide active account management for specialty pharmacies, wholesalers/distributors, 3PL and other key trade partners to support product availability, service performance, and operational excellence

Establish, monitor, and manage key performance indicators, service-level expectations, inventory metrics, dispense data, and reporting requirements for channel partners; hold partners accountable while maintaining strong relationships

Ensure patient accessibility to product through trade partners and specialty pharmacies while supporting compliant processes and appropriate operational controls

Lead cross-functional teams with Patient Services, Commercial Operations/Analytics, Finance, IT, Field Sales, Legal/Compliance, Contracting, and Supply Chain to implement channel strategies, improve workflows, strengthen data quality, and track progress against established goals

Serve as the lead negotiator for enterprise-level contracts with major Wholesalers, Specialty Distributors, and Specialty Pharmacies to optimize channel fee structures and service requirements

Develop and implement an optimized distribution and contracting strategy which can anticipate industry shifts and proactively adapt the distribution model to maintain a competitive advantage

Oversee launch readiness for activities within the Trade and Distribution as we prepare for the launch our lead clinical asset as well as all pipeline assets and lifecycle management initiatives

Lead transformation initiatives in Trade & Distribution including process redesign, systems modernization, vendor optimization, and automation to improve efficiency, scalability, and data accuracy

Forecasting, Financial Governance & GTN

Own the trade-related components of the Gross-to-Net (GTN) strategy, providing executive leadership with visibility into channel costs, inventory fluctuations, and potential financial risks

Drive the integration of channel data into enterprise forecasting models to ensure high-accuracy demand planning and inventory management

Implement advanced analytics to monitor channel health, utilizing data-driven insights to mitigate product diversion, stockpiling, or supply disruptions

Establish and evolve KPIs and performance frameworks to assess and guide trade performance and strategic effectiveness

Collaborate with finance and other internal stakeholders to set up and manage systems/processes to track order to cash as well as fulfill government reporting obligations

Leadership and Organizational Influence

Collaborate with other members of the U.S. Market Access, Finance, and Commercial Operation, Supply Chain, Finance and other cross-functional team members to align trade strategy with broader corporate financial and patient access goals

Manage external partners and vendors to ensure effective and efficient management of day-to-day U.S. Trade and Distribution operations

Demonstrate high levels of emotional intelligence, situational awareness, and ability to build and influence a positive team culture

Actively participate and contribute to the Market Access leadership team and other formal or informal cross-functional teams as needed

Ideal Candidate Profile >>>

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.

Education and Required Skills

Education:  Bachelor’s degree required; MBA or advanced degree in supply chain management or healthcare administration preferred

Experience: 15+ years of progressive leadership experience in pharmaceutical trade and distribution, with a proven track record of working with partners in specialty pharmacy, distribution and 3PL

Therapeutic Knowledge:  Experience with oral oncology products is required and knowledge of the oncology provider space, specifically large and complex customers (GPOs, Institutions, IDNs, etc…) will be essential

Technical Expertise:  Knowledge and experience with key Trade and Distribution technologies, well as with relevant federal and state legislation

Strategic Negotiation:  Demonstrated success in leading high-stakes negotiations with national wholesalers and large-scale oncology providers

Launch Leadership:  Extensive experience leading trade strategy for successful U.S. product launches, particularly in the oncology drug space, with relevant and recent  experience launching oral oncology products

Cross-Functional Collaboration Skills: Demonstrated ability to work cross-functionally and to influence stakeholders with the aim of creating and maintaining an optimized distribution system/processes which optimizes GTN and prioritizes customer service

Performance Management: Works with vendors and external partners to drive performance while maintaining relationships

Analytical Skills: Set and maintain clear performance objectives and KPIs which ensure alignment with broader US commercial and global market access priorities

The base pay range for this position is expected to be $270,000 - $300,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

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